Tes Pharma, a biotech company focused on delivering first-in-class therapeutics for high unmet medical needs in oncology renal and metabolic diseases based in OpenZone, today announced the renewal of its research and development collaboration with Intercept Pharmaceuticals, Inc. (Intercept), a wholly owned subsidiary of Alfasigma S.p.A. focused on the development and commercialization of novel therapeutics to treat rare and serious liver diseases.
As part of the collaboration, which began in 2015, Intercept purchased from Tes Pharma the rights to INT-787, a selective next generation Farnesoid X Receptor (FXR) agonist that showed strong anti-fibrotic and anti-inflammatory effects in animal models and is currently in clinical development for the treatment of severe alcohol-associated hepatitis (sAH).